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Research Assistant - Peng Lab

Job Description

Research Assistant - Peng Lab

The Department of Molecular Biomedical Sciences trains doctors of veterinary medicine and graduate students interested in research-based careers focused on the discovery of new knowledge about animal and human health and disease and using those findings to enhance animal and human health and well-being. Students get in depth knowledge of the molecular mechanisms of disease, and experience in the development of new procedures which enable its prevention, diagnosis, and treatment.

Our faculty are recognized experts in the fields of cell biology and physiology, cancer biology, developmental biology, environmental science and toxicology, genomics, infectious diseases, neuroscience, pharmacology, radiology, and reproductive biology. Our goals are to advance veterinary medical science through innovative basic and applied research, and by mentoring and inspiring students, providing world-class clinical and diagnostic services, and offering the public the latest knowledge through innovative extension and engagement activities.

Our research faculty work in state-of-the-art research facilities including a transgenic mouse facility where graduate students can participate in research projects related to mouse and animal genomics.

A number of graduate programs are available to students interested in working with faculty in the Department of Molecular Biomedical Sciences. In addition, faculty oversee following clinical sections: anesthesia, clinical nutrition, pharmacology, and the radiology residency.

Essential Job Duties

The Peng Lab uses systems approaches to better understand pathogen-host-microbiome interactions and microbial pathogenesis. The goal is to uncover underlying molecular mechanisms of microbial pathogenesis and to identify targets of intervention as well as biomarkers for clinical applications. We focus on computational analysis of high-throughput omics data combined with experimental validation. The Lab is housed in the College of Veterinary Medicine (CVM) Research Building located at the NCSU Biomedical Centennial Campus, and is part of NCSU Bioinformatics Research Center.

The incumbent of this position will develop and perform wet-lab research in the lab. This candidate will maintain animal and human cell lines, perform in vitro infections with human and animal pathogens, conduct high-throughput DNA and RNA sequencing using cell culture, animal model and human clinical samples, and high-throughput library screen in vitro. The candidate will assist the development of research projects and hypotheses, interpret and evaluate data, compile experimental results and findings for publication, and contribute preliminary data to research grant proposals. The successful candidate will also be responsible for overseeing the day-to-day operations of our experimental laboratory.

The selected individual will understand the rationale for the research, and perform related experiments to test research hypotheses. Research activities include independent management of research projects, experimental assay and protocol development, and designing and carrying out experiments.

Duties include the following:
  • Infection of cell cultures with human and animal pathogens such as HIV/SIV and influenza
  • RNA and DNA isolation from different cell and tissue types
  • Determination of nucleic acid concentrations and integrity on research samples
  • Construction of libraries for RNA and DNA deep sequencing
  • Performing deep sequencing runs and qRT-PCR assays
  • Performing high-throughput library screen in vitro
  • Implementing, developing and optimizing custom experimental protocols
  • Independently maintaining lab records and entering experimental results into the web-based LIMS
  • Managing sample acquisition from collaborating research laboratories
  • Maintaining sample inventory
  • Participating in developing methodology, protocols and troubleshooting
  • Presenting experimental results to other laboratory members
  • Contributing to publications, reports, and draft manuscripts

This position is currently funded through September 2019 and, pending further funding, could end at that time.

Other Work/Responsibilities


Minimum Education/Experience

Relevant Master?s degree, or relevant Bachelor?s and 3 or more years of relevant experience will be considered.

Departmental Required Skills

Strong organizational skills and attention to detail.
Desire and willingness to learn, develop, and execute new experimental techniques and take on challenging scientific problems.
Ability to work independently as well as contribute to a supportive team environment.
Strong analytical skills
Excellent oral and written communication skills.
Ability to coordinate and prioritize multiple, concurrent projects.
Knowledge of laboratory equipment and procedures.
Accurate record keeping and data management skills.

Preferred Experience, Skills, Training/Education


Required License or Certification


Special Instructions

Applications should include a cover letter, a current resume or curriculum vitae, and contact information for three or more references.

Job Open Date

Must Be Open Until

Positions will be posted until 5:00 PM ET on this date. Positions remaining posted after this date are still accepting applications but may close at any time.

Is this position partially or fully funded on ARRA stimulus monies?

Proposed Hire Date


NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran.

Individuals with disabilities requiring disability-related accommodations in the application and interview process, please call 919-515-3148.
Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. If highest degree is from an institution outside of the U.S., final candidates are required to have their degree verified at Degree must be obtained prior to start date.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.


Research Assistant - Peng Lab